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India Unveils First Indigenous CRISPR Gene Therapy 'BIRSA 101' for Sickle Cell Disease Amidst Broader Scientific Growth

November 22, 2025

India has marked a significant scientific milestone with the launch of "BIRSA 101," its first indigenous CRISPR-based gene therapy specifically designed to combat sickle cell disease. This breakthrough, developed by CSIR-IGIB, aims to provide an affordable and accessible treatment, particularly benefiting tribal populations. Union Minister Dr. Jitendra Singh highlighted the nation's expanding scientific capabilities and its commitment to fostering innovation, referencing the upcoming India International Science Festival (IISF 2025). Simultaneously, a new study revealed a concerning rise in India's average temperature over the last decade, underscoring urgent environmental challenges.

Question 1 of 13

1. What is the name of India's first homegrown CRISPR-based gene therapy targeting sickle cell disease?

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